Wednesday, 14 July 2010

A NEUROSCIENTIST UNCOVERS A DARK SECRET

Nice piece for NPR from Barbara Bradley Hagerty about the deficits in orbito-frontal cortex (see my stuff on the social brain in Not A Chimp) in psychopaths - by neuroscientist James Fallon. Really interesting spooky story because Fallon used his own family to look for abnormalities in o-r cortex and variants of the gene MAO-A - which are known to predispose to violence - because lurking in his family's history were a number of known murderers! His extant family turned out to be abnormal with the excerption of himself. Fallon discovered, to his discomfort, that his orbito-frontal cortex bore all the signs of psychopathy, while he also proved positive for the presence of the notorious short variant of MAO-A! However the vital gene-environment interaction - a violent and abused childhood - was the final ingredient missing from Fallon's mix. He had experienced a blissful childhood - which is why he turned into a loving husband and prominent scientist - and not a violent murderer!